The European Commission has tasked ECHA to make scientific evaluations, within the scope of the Carcinogens, Mutagens or Reprotoxic Substances Directive, on the toxicological profiles of the following substances in relation to their adverse health effects on workers:

• N-(Hydroxymethyl)acrylamide;
• Ethylene dibromide (EDB) or 1,2-Dibromoethane;
• Anthraquinone;
• 1,3-Propanesultone; and
• Oximes: Butanone oxime and Acetone oxime.

These evaluations are to be finalised by April 2026 and will, where appropriate, include proposals for occupational exposure limit values, biological limit and guidance values as well as notations.